PBL2 Essay Example | Topics and Well Written Essays - 1500 words

PBL2 - Essay Example The ischemic necrosis of kidneys gradually heals by undergoing progressive fibrous scarring (Alpers, pg. 1012). Destruction of extracellular matrix occurs. The regenerative capacity of renal tissue is maximal in cortical tubules, less in medullary tubules, and nonexistent in glomeruli. Hence this is the correct answer. B: Granuloma formation: Granulomas are formed following chronic inflammation and are encountered in some immunological mediated reactions, infections and some non-infections conditions. Some of the common conditions in which granulomatous inflammation occurs are tuberculosis, sarcoidosis, cat-scratch disease, leprosy and syphilis. The granuloma consists macrophages mainly (Kumar, pg.83-84). Hence this is not the correct answer. C: Liquefaction: Liquefaction or liquefactive necrosis is a condition in which the affected cell is completely digested due to powerful hydrolytic enzymes. It usually occurs in fungal and bacterial infections and causes formation of abscess. Also, ischemic injury in brain causes liquefaction (Mitchell, 138). Hence this is not the correct answer. D: Metastatic calcification: Deposition of calcium salts in otherwise normal tissue is known as metastatic calcification. It occurs due to elevated calcium levels. It is commonly seen in the kidneys and lungs. Hence this is not the correct answer. A 25 year old-woman sustains a deep laceration over the right forearm in a motorcycle accident. The wound is cleaned and sutured. During the next 3 months, the wound heals with formation of a linear scar. Which of the following nutritional factors is required for proper collagen assembly in the scar tissue of the patient? A. Folic acid: Folate, the useful form of folic acid is an essential nutrient for the production and maintenance of new cells because it is needed for the replication of DNA. It is not useful for collagen production. Hence this is not the correct